BLENREP is a prescription medicine used to treat adults with multiple myeloma who have received at least 4 prior medicines to treat multiple myeloma, and their cancer has come back or did not respond to prior treatment. It is not known if BLENREP is safe and effective in children.

This Horizons Infosheet contains information about belantamab mafodotin, a drug being investigated for the treatment of myeloma. Publication date: April 2020 Last updated: November 2020 Review date: May 2021

Research Triangle Park See full prescribing information for. BLENREP. BLENREP (belantamab mafodotin-blmf) for injection, for intravenous use. Initial U.S. Approval: 2020. WARNING: The U.S. Food and Drug Administration has granted Emergency Use Authorization (EUA) for bamlanivimab and etesevimab together and bamlanivimab alone Nov 9, 2020 Blenrep® [prescribing information]. Research Triangle Park, NC. GlaxoSmithKline. 2020.

Belantamab package insert

Blenrep is used to treat multiple myeloma in adults. This medicine is given after at least 4 other treatments did not work or have stopped working. Belantamab mafodotin (BLENREP^™; belantamab mafodotin-blmf) is a first-in-class monoclonal antibody-drug conjugate (ADC) that has been developed for the treatment of multiple myeloma by GlaxoSmithKline. The ADC comprises an antibody targeting B-cell maturation antigen (BCMA) conjugated to … 2020-09-16 · Belantamab mafodotin (BLENREP™; belantamab mafodotin-blmf) is a first-in-class monoclonal antibody-drug conjugate (ADC) that has been developed for the treatment of multiple myeloma by GlaxoSmithKline.

2020-07-14

Brentford, Middlesex, UK; GlaxoSmithKline, Ltd; August 2020. Accessed August 2020.

Belantamab mafodotin is the first BCMA-targeted antibody-drug conjugate with a humanized anti-BCMA monoclonal antibody (mAb) conjugated to the microtubule inhibitor mafodotin. 2,5 Belantamab mafodotin specifically binds to BCMA and eliminates myeloma cells by a multimodal mechanism.

Lonial S, Lee HC, Badros A, et al. Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM—2): a … GlaxoSmithKline plc (LSE/NYSE: GSK) announced the US Food and Drug Administration (FDA) has approved BLENREP (belantamab mafodotin-blmf) as a monotherapy treatment for adult patients with relapsed or refractory multiple myeloma who have received at least four prior therapies including an anti-CD38 monoclonal antibody, a proteasome inhibitor and an immunomodulatory agent.

2,5 Belantamab mafodotin specifically binds to BCMA and eliminates myeloma cells by a multimodal mechanism.
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Publication date: April 2020 Last updated: November 2020 Review date: May 2021 FDA Approves GSK’s BLENREP (belantamab mafodotin-blmf) for the Treatment of Patients with Relapsed or Refractory Multiple Myeloma. The FDA granted a priority review to belantamab mafodotin for the treatment of heavily pre-treated patients with relapsed or refractory multiple myeloma, according to GlaxoSmithKline. 1.

See full prescribing information for complete boxed warning. BLENREP Belantamab Mafodotin (Belamaf) Accelerated Approval for Patients with Relapsed or Refractory Multiple Myeloma July 14, 2020 GlaxoSmithKline Oncologic Drug Advisory Committee 2021-04-01 2021-01-01 Belantamab mafodotin is a B-cell maturation antigen (BCMA)-directed antibody and microtubule inhibitor conjugate indicated for the treatment of adult patients with relapsed or refractory multiple BLENREP is a prescription medicine used to treat adults with multiple myeloma who have received at least 4 prior medicines to treat multiple myeloma, and their cancer has come back or did not respond to prior treatment. It is not known if BLENREP is safe and effective in children. BLENREP is indicated for the treatment of adults with relapsed or refractory multiple myeloma who have received at least 4 prior therapies, including an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulatory agent.
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Early data from the DREAMM-6 study suggest that the combination of belantamab mafodotin, bortezomib, and dexamethasone is active in patients with relapsed or refractory multiple myeloma (MM). 1 These findings were presented by Ajay Nooka, MD, of the Winship Cancer Institute at Emory University in Atlanta, Georgia, as part of the ASCO20 Virtual Scientific Program.

WARNING: The U.S. Food and Drug Administration has granted Emergency Use Authorization (EUA) for bamlanivimab and etesevimab together and bamlanivimab alone Nov 9, 2020 Blenrep® [prescribing information]. Research Triangle Park, NC. GlaxoSmithKline. 2020. Belantamab mafodotin-blmf. Adverse effects.